"I never imagined a time when craft beer would become so mainstream,” said Rene Greff, co-owner of Arbor Brewing Company brewpub in Ann Arbor and ABC Microbrewery in Ypsilanti. In 1995, when Rene and her husband, Matt Greff, opened the brewpub on Washington Street, craft beer was anything but mainstream. A few brands were paving the way, including Samuel Adams in Boston, Sierra Nevada and Anchor Brewing in California, and Bell’s Brewery in Michigan, but American beer sales and consciousness were dominated by light, insipid lagers produced by mega-breweries like Anheuser Busch, Coors, and Miller.